Synthesis and biological evaluation of novel phenanthridinyl piperazine triazoles via click chemistry as anti-proliferative agents

QR Code

Synthesis and biological evaluation of novel phenanthridinyl piperazine triazoles via click chemistry as anti-proliferative agents

The preliminary results describe synthesis of a series of novel 6-(4-((substituted-1H-1,2,3-triazol-4-yl)methyl)piperazin-1-yl)phenanthridine analogs using hybrid approach employing copper(I)-catalyzed azide-alkyne cycloaddition and their evaluation as antiproliferative agents against four cancer ce...

書目詳細資料
發表在:	Medicinal Chemistry Research
主要作者:	Nagesh H.N.; Suresh N.; Prakash G.V.S.B.; Gupta S.; Rao J.V.; Sekhar K.V.G.C.
格式:	Article
語言:	English
出版:	Birkhauser Boston 2015
在線閱讀:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-84926482705&doi=10.1007%2fs00044-014-1142-6&partnerID=40&md5=d57036eae9a7303722f809c4acfe5526

相似書籍

Synthesis and biological evaluation of novel phenanthridinyl piperazine triazoles via click chemistry as anti-proliferative agents
由: 2-s2.0-84926482705
出版: (2015)

Synthesis and evaluation of novel 1, 2, 4-substituted triazoles for urease and anti-proliferative activity
由: 2-s2.0-85124607308
出版: (2022)

Natural diterpene pyrones: Chemistry and biology
由: 2-s2.0-85073488951
出版: (2019)

Adoption and performance of click and mortar retailers: Malaysia evidence
由: Ali A.; Omar N.; Daud N.M.; Mohamed I.S.
出版: (2012)

International Consensus for the Dosing of Corticosteroids in Childhood-Onset Systemic Lupus Erythematosus With Proliferative Lupus Nephritis
由: 2-s2.0-85122264560
出版: (2022)

Systematic review: The effectiveness of physical treatments on thoracic outlet syndrome in reducing clinical symptoms
由: Lo C.N.C.; Bukry S.A.; Alsuleman S.; Simon J.V.
出版: (2011)

Synthesis of piperazine sulfonamide analogs as diabetic-II inhibitors and their molecular docking study
由: 2-s2.0-85032929001
出版: (2017)

Can Brick-and-Click Stores Yield Returning Online Customers? Assessing In-house Logistics Service Quality (LSQ) of Multi-channel Retailers
由: 2-s2.0-85168463058
出版: (2023)

Solubility of CO2 in aqueous piperazine and its modeling using the Kent-Eisenberg approach
由: 2-s2.0-1042266959
出版: (2004)

Fostering critical thinking in pharmaceutical chemistry: A cross-sectional study
由: Choo C.-Y.; Ming L.C.; Tan C.S.
出版: (2022)

Antiplasmodial anthraquinones from medicinal plants: The chemistry and possible mode of actions
由: Osman C.P.; Ismail N.H.
出版: (2018)

Antiplasmodial anthraquinones from medicinal plants: The chemistry and possible mode of actions
由: 2-s2.0-85059548311
出版: (2018)

Synthesis and biological evaluation of heterocyclic 1,2,4-triazole scaffolds as promising pharmacological agents
由: 2-s2.0-85099564407
出版: (2021)

Synthesis and Structure-Activity Relationship of 1-(2-Furoyl)Piperazine Bearing Benzamides as Butyrylcholinesterase Inhibitors
由: 2-s2.0-85091726412
出版: (2020)

Synthesis of some unique carbamate derivatives bearing 2-furoyl-1-piperazine as a valuable therapeutic agents
由: 2-s2.0-85016141011
出版: (2017)

Synthesis, biological evaluation, and molecular docking study of novel 1,2,4-substituted triazoles as inhibitors of alzheimer’s disease
由: 2-s2.0-85136203736
出版: (2022)

Synthesis of some N-sulfonated derivatives of 1-[(E)-3-phenyl-2-propenyl]piperazine as suitable antibacterial agents
由: 2-s2.0-85090169024
出版: (2020)

BSA Binding, molecular docking and in vitro biological screening of some new 1, 2, 4-triazole heterocycles bearing azinane nucleus
由: 2-s2.0-85077920867
出版: (2020)

Synthesis and structure-activity relationship of 1-[(E)-3-phenyl-2-propenyl] piperazine derivatives as suitable antibacterial agents with mild hemolysis
由: 2-s2.0-85105482274
出版: (2019)

Synthesis of triazole Schiff bases: Novel inhibitors of nucleotide pyrophosphatase/phosphodiesterase-1
由: 2-s2.0-84908377390
出版: (2014)

Development of Organic Semiconductor Materials for Organic Solar Cells via the Integration of Computational Quantum Chemistry and AI-Powered Machine Learning
由: Shafian, et al.
出版: (2025)

Development of Organic Semiconductor Materials for Organic Solar Cells via the Integration of Computational Quantum Chemistry and AI-Powered Machine Learning
由: Shafian S.; Mohd Salehin F.N.; Lee S.; Ismail A.; Mohamed Shuhidan S.; Xie L.; Kim K.
出版: (2025)

Development of Organic Semiconductor Materials for Organic Solar Cells via the Integration of Computational Quantum Chemistry and AI-Powered Machine Learning
由: 2-s2.0-85214905984
出版: (2025)

POMICS: A simulation disease model for timing fungicide applications in management of Powdery Mildew of Cucurbits
由: Sapak Z.; Salam M.U.; Minchinton E.J.; MacManus G.P.V.; Joyce D.C.; Galea V.J.
出版: (2017)

Design, synthesis of triazole-based scaffolds, N-(substitutedphenyl)-2-(5-(4-methoxyphenyl)-4-phenyl-4H-1,2,4-triazol-3-ylthiol)acetamides: As potential anti-cholinesterase agents for neurodegenerative diseases
由: 2-s2.0-85160806262
出版: (2023)

A preliminary study into the effect of oxide chemistry on the bonding mechanism of cold-sprayed titanium dioxide coatings on SUS316 stainless steel substrate
由: Omar N.I.B.; Mohamed S.B.; Yusuf Y.B.; Rahim T.B.A.; Mustafa Z.B.; Ismail S.B.; Bakar I.A.B.A.; Selvamani S.
出版: (2022)

DFIG HVDC based wind farms system profile improvement under grid faults
由: Hannoon N.M.S.; Chowdary P.S.R.; Ananth D.V.N.; Chakravarthy V.V.S.S.S.
出版: (2022)

AN ANALYSIS OF INFORMATION VISUALISATION DESIGN BASED ON COGNITIVE THINKING AND VISUAL THINKING
由: Yang R.; Abidin S.Z.; Vermol V.V.
出版: (2024)

Power Quality Conditioning due to Flickering Loads with Shunt Active Power Filter using Fuzzy-Granular Controller Method
由: Hannoon N.M.S.; Ananth D.V.N.; Hiday N.; Chowdary P.S.R.; Chakravarthy V.V.S.S.S.
出版: (2021)

S-substituted derivatives of 1,2,4-triazol-3-thiol as new drug candidates for type II diabetes
由: 2-s2.0-85047939044
出版: (2018)

Building process summary
由: Torrance V.
出版: (1997)

Charting new horizons: a bibliometric analysis of the landscape of grounded theory in Indonesian communication studies
由: Wan Noordin W.N.; Sukmayadi V.; Christi T.V.
出版: (2025)

Determinants of supply chain responsiveness among firms in the manufacturing industry in Malaysia
由: Rajagopal P.; Azar N.A.Z.; Bahrin A.S.; Appasamy G.; Sundram V.P.K.
出版: (2016)

Supply chain responsiveness in an asian global electronic manufacturing firm: ABX Energy (M)
由: Sundram V.P.K.; Rajagopal P.; Azar N.A.Z.; Bahrin A.S.; Appasamy G.
出版: (2018)

Exploratory factor analysis: Blended motivation of Malay students Learning Mandarin as a Foreign Language
由: Tan T.G.; Ismail H.N.; Ooi A.E.
出版: (2016)

In vitro and in silico assessment of bioactivity properties and pharmacokinetic studies of new 3,5-disubstituted-1,2,4-triazoles
由: 2-s2.0-85145590047
出版: (2023)

Real-time power quality measurement audit of government building – A case study in compliance with IEEE 1159
由: Ananth D.V.N.; Hannoon N.; Yunus M.S.B.M.; Jamaludin M.H.B.; Sameer Charavarthy V.V.S.S.; Chowdary P.S.R.
出版: (2023)

Synthesis of acetamide derivatives of 1,2,4-triazole bearing azinane and their binding interactions with bovine serum albumin using spectroscopic techniques
由: Iqbal J.; Ur-Rehman A.; Abbasi M.A.; Siddiqui S.Z.; Khalid H.; Laulloo S.J.; Joondan N.; Taupass A.B.; Rasool S.; Shah S.A.A.
出版: (2018)

Discovery of Dual Inhibitors of Acetyl and Butrylcholinesterase and Antiproliferative Activity of 1,2,4-Triazole-3-thiol: Synthesis and In Silico Molecular Study
由: 2-s2.0-85087042710
出版: (2020)

Α-Glucosidase inhibitory potential and hemolytic evaluation of newly synthesized 3, 4, 5-trisubstituted-1, 2, 4-triazole derivatives
由: 2-s2.0-85077924129
出版: (2019)