Synthetic indole Mannich bases: Their ability to modulate in vitro cellular immunity

The synthetic indole Mannich bases 1-13 have been investigated for their ability to modulate immune responses measured in vitro. These activities were based on monitoring their affects on T-lymphocyte proliferation, reactive oxygen species (ROS), IL (interleukin)-2, IL-4, and nitric oxide production...

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Bibliographic Details
Published in:Bioorganic Chemistry
Main Author: Mesaik M.A.; Khan K.M.; Rahim F.; Taha M.; Haider S.M.; Perveen S.; Khalid A.S.; Abdalla O.M.; Soomro S.; Voelter W.
Format: Article
Language:English
Published: Academic Press Inc. 2015
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-84929625705&doi=10.1016%2fj.bioorg.2015.05.003&partnerID=40&md5=023d29260820d64c8fb0644fb0c650da