Oxidised low density lipoprotein causes human macrophage cell death through oxidant generation and inhibition of key catabolic enzymes

Oxidised low density lipoprotein (oxLDL) is thought to be a significant contributor to the death of macrophage cells observed in advanced atherosclerotic plaques. Using human-derived U937 cells we have examined the effect of cytotoxic oxLDL on oxidative stress and cellular catabolism. Within 3 h of...

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Bibliographic Details
Published in:International Journal of Biochemistry and Cell Biology
Main Author: Katouah H.; Chen A.; Othman I.; Gieseg S.P.
Format: Article
Language:English
Published: Elsevier Ltd 2015
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-84940866610&doi=10.1016%2fj.biocel.2015.08.001&partnerID=40&md5=267b6e1a3195735ce995c7f5a8940269