Calreticulin mediates an invasive breast cancer phenotype through the transcriptional dysregulation of p53 and MAPK pathways

QR Code

Calreticulin mediates an invasive breast cancer phenotype through the transcriptional dysregulation of p53 and MAPK pathways

Background: The introduction of effective novel biomarkers of invasion and metastasis is integral for the advancement of breast cancer management. The present study focused on the identification and evaluation of calreticulin (CRT) as a potential biomarker for breast cancer invasion. Methods: Two-di...

Full description

Bibliographic Details
Published in:	Cancer Cell International
Main Author:	Zamanian M.; Qader Hamadneh L.A.; Veerakumarasivam A.; Abdul Rahman S.; Shohaimi S.; Rosli R.
Format:	Article
Language:	English
Published:	BioMed Central Ltd. 2016
Online Access:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-84979695866&doi=10.1186%2fs12935-016-0329-y&partnerID=40&md5=0a488b522fda931809b93dc3eb5bfb5b

Similar Items

Damnacanthal is a potent inducer of apoptosis with anticancer activity by stimulating p53 and p21 genes in MCF-7 breast cancer cells
by: Aziz M.Y.A.; Omar A.R.; Subramani T.; Yeap S.K.; Ho W.Y.; Ismail N.H.; Ahmad S.; Alitheen N.B.
Published: (2014)

Reverting TP53 Mutation in Breast Cancer Cells: Prime Editing Workflow and Technical Considerations
by: Abuhamad A.Y.; Mohamad Zamberi N.N.; Sheen L.; Naes S.M.; Mohd Yusuf S.N.H.; Ahmad Tajudin A.; Mohtar M.A.; Amir Hamzah A.S.; Syafruddin S.E.
Published: (2022)

Magnetic Resonance Imaging Phenotypes of Breast Cancer Molecular Subtypes: A Systematic Review
by: Ab Mumin N.; Ramli Hamid M.T.; Wong J.H.D.; Rahmat K.; Ng K.H.
Published: (2022)

P53 and cyclin B1 mediate apoptotic effects of apigenin and rutin in ERα+-breast cancer MCF-7 cells
by: Abdul Hamid Hasani N.; Mohd Amin I.; Kamaludin R.; Nik Mohd Rosdy N.M.M.; Johari Ibahim M.; Sheikh Abdul Kadir S.H.
Published: (2018)

Ranibizumab inhibits human tenon's fibroblast proliferation via p21 dependent p53 mechanisms; [Ranibizumab merencat percambahan fibroblas tenon manusia melalui mekanisme p21 bersandar p53]
by: Noh S.M.M.; Kadir S.H.S.A.; Vasudevan S.
Published: (2021)

CYP2D6 Genetic Polymorphisms and Phenotypes in Different Ethnicities of Malaysian Breast Cancer Patients
by: Chin F.W.; Chan S.C.; Abdul Rahman S.; Noor Akmal S.; Rosli R.
Published: (2016)

Suppression of PGE2 production via disruption of MAPK phosphorylation by unsymmetrical dicarbonyl curcumin derivatives
by: Mohd Aluwi M.F.F.; Rullah K.; Haque M.A.; Yamin B.M.; Ahmad W.; Amjad M.W.; Leong S.W.; Fahmizar N.A.; Jalil J.; Abas F.; Ismail N.H.; Jantan I.; Lam K.W.
Published: (2017)

Magnetic resonance imaging features of invasive breast cancer association with the tumour stromal ratio
by: Mumin N.A.; Hamid M.T.R.; Hamid S.A.; Chiew S.-F.; Saman M.S.A.; Rahmat K.
Published: (2023)

Magnetic resonance imaging features of invasive breast cancer association with the tumour stromal ratio
by: Ab Mumin, et al.
Published: (2023)

Phenotype adaptation of Kluyveromyces marxianus for enhanced conversion of biomass into xylitol
by: Manaf S.F.A.; Luthfi A.A.I.; Nasoha N.Z.; Engliman N.S.; Jamali N.S.; Tan J.P.
Published: (2024)

Phenotype adaptation of Kluyveromyces marxianus for enhanced conversion of biomass into xylitol
by: Manaf, et al.
Published: (2024)

Enhancement of oxidative DNA damage and alteration of p53, bax, and Bcl-2 protein expressions following low dose radiation exposure
by: Saad W.M.M.; Mohammad M.K.A.; Mohamed M.I.; Razak H.R.A.
Published: (2017)

A rare invasive male breast cancer of nonspecific type presenting at a primary care clinic: Importance of early diagnosis and management
by: Mansoor N.S.; Arifin F.; Kornain N.K.M.; Razalli M.M.
Published: (2023)

A rare invasive male breast cancer of nonspecific type presenting at a primary care clinic: Importance of early diagnosis and management
by: Mansoor, et al.
Published: (2023)

Paroxysmal, exercise-induced, diurnally fluctuating dystonia: Expanding the phenotype of SPG8
by: Mulroy E.; Magrinelli F.; Mohd Fauzi N.A.; Kutty S.K.; Latorre A.; Bhatia K.P.
Published: (2021)

Aloe emodin induces apoptosis in ER+-breast cancer cells; MCF-7 through IGF-1R signalling pathway
by: Amin I.M.; Kamaludin R.; Yeap S.K.; Isa M.R.; Mohd Rosdy N.M.M.N.; Siran R.; Kadir S.H.S.A.; Hasani N.A.H.
Published: (2015)

Isolation, peroxisome proliferator-activated receptor-gamma transcription, glucose uptake, and molecular docking of tetramethoxyflavonoids from the leaves of Rourea mimosoides (Vahl) Planch
by: Osman C.P.; Somat N.A.; Zahari Z.; Imran S.; Adenan M.I.
Published: (2021)

The Economic Burden of Candidemia and Invasive Candidiasis: A Systematic Review
by: Wan Ismail W.N.A.; Jasmi N.; Khan T.M.; Hong Y.H.; Neoh C.F.
Published: (2020)

Exploring the transcription start sites and other genomic features facilitates the accurate identification and annotation of small RNAs across multiple stress conditions in Mycobacterium tuberculosis
by: Cheah H.-L.; Citartan M.; Lee L.-P.; Ahmed S.A.; Salleh M.Z.; Teh L.K.; Tang T.-H.
Published: (2024)

Clinical phenotypes and heath-related quality of life of COPD patients in a rural setting in Malaysia- A cross-sectional study
by: Chai C.-S.; Mos S.B.; Ng D.-L.-C.; Goh G.-M.-K.-C.; Su A.-T.; Ibrahim M.A.B.; Musa A.N.B.; Tan S.-B.; Pang Y.-K.; Liam C.-K.
Published: (2020)

Office based non-invasive diagnostic technique for acquired tracheoesophageal fistula
by: Rajendram N.; Mansor M.; Rahim N.A.; Bakar M.Z.A.; Sobani M.A.
Published: (2024)

Anti-inflammatory effects of high-density lipoprotein via regulation of nitric oxide synthase expression and Nf-κb transcription in activated human endothelial cells
by: Wan Yusoff W.N.; Chua Y.-A.; Froemming G.R.A.; Ali A.M.; Nawawi H.
Published: (2017)

Human and animal invasive muscular sarcocystosis in Malaysia - Recent cases, review and hypotheses
by: Tappe D.; Abdullah S.; Heo C.C.; Kannan Kutty K.; Latif B.
Published: (2013)

Clinical Performance of Reverse Transcription Loop-mediated Isothermal Amplification COVID-19 Assay on Gold-nanoparticle-modified Screen-printed Carbon Electrode Using Differential Pulse Voltammetry
by: Zulhairee M.; Zain R.M.; Nor A.C.M.; Jafar N.F.; Noh M.F.M.; Noorden M.S.A.; Nordin A.N.; Rahim R.A.; Gunawan T.S.; Chin L.Y.; Mohd Y.; Azman N.A.; Zain Z.M.
Published: (2023)

Invasion characteristics of a Plasmodium knowlesi line newly isolated from a human
by: Amir A.; Russell B.; Liew J.W.K.; Moon R.W.; Fong M.Y.; Vythilingam I.; Subramaniam V.; Snounou G.; Lau Y.L.
Published: (2016)

Evaluation of risk factors for prolonged invasive mechanical ventilation in paediatric intensive care unit (PICU)
by: Ismail I.; Yap B.W.; Abidin A.S.Z.
Published: (2017)

Pharmacoeconomic evaluation of micafungin versus caspofungin as definitive therapy for candidaemia and invasive candidiasis (IC) in Turkey
by: Neoh C.F.; Senol E.; Kara A.; Dinleyici E.C.; Turner S.J.; Kong D.C.M.
Published: (2018)

Epidemiological observations of invasive group B Streptococcus infections in six major hospitals in Peninsular Malaysia
by: Muthanna, et al.
Published: (2024)

Non-invasive diagnosis of risk in dengue patients using bioelectrical impedance analysis and artificial neural network
by: Ibrahim F.; Faisal T.; Mohamad Salim M.I.; Taib M.N.
Published: (2010)

Reply to “Critique of a Study on Breast Ultrasound as an Adjunct to Breast Tomosynthesis for Breast Cancer Screening and Diagnosis”
by: Rahmat K.; Ab Mumin N.
Published: (2024)

Reply to Critique of a Study on Breast Ultrasound as an Adjunct to Breast Tomosynthesis for Breast Cancer Screening and Diagnosis
by: Rahmat, et al.
Published: (2024)

Abbreviated breast magnetic resonance imaging (MRI) or digital breast tomosynthesis for breast cancer detection in dense breasts? A retrospective preliminary study with comparable results
by: Hamid, et al.
Published: (2024)

Abbreviated breast magnetic resonance imaging (MRI) or digital breast tomosynthesis for breast cancer detection in dense breasts? A retrospective preliminary study with comparable results
by: Ramli Hamid M.T.; Ab Mumin N.; Abdul Hamid S.; Ahmad Saman M.S.; Rahmat K.
Published: (2024)

Construction of tvet students' career profile pathways
by: Mohd Nor A.R.; Rasul M.S.; Amat S.
Published: (2021)

Sustainable manufacturing 4.0-pathways and practices
by: Gholami H.; Abu F.; Lee J.K.Y.; Karganroudi S.S.; Sharif S.
Published: (2021)

Interaction of Hemoglobin-F, Hemoglobin-A2, Hemoglobin Subunits and Clinical Phenotypes of β-Thalassemia with the Levels of Early-eluting Unknown Peaks during High-performance Liquid Chromatography Analysis of Hemoglobin
by: Abdullah U.Y.H.; Ibrahim A.M.; Ibrahim H.M.; Azzubaidi M.S.; bin Noorizhab M.N.F.; Jassim H.M.; Kek T.L.
Published: (2024)

Making white spots disappear! Do minimally invasive treatments improve incisor opacities in children with molar-incisor hypomineralisation?
by: Warner C.; Hasmun N.N.; Elcock C.; Lawson J.A.; Vettore M.V.; Rodd H.D.
Published: (2022)

Etching Time On Structural And Electrical Properties Of Porous Silicon Sers Substrates For Non-Invasive Dengue-Ns1 Detection
by: Ismail N.F.; Ismail L.N.; Lee K.Y.; Zulhanip A.Z.; Hadis N.S.M.; Radzol A.R.M.
Published: (2021)

Three Members of Transmembrane-4-Superfamily, TM4SF1, TM4SF4, and TM4SF5, as Emerging Anticancer Molecular Targets against Cancer Phenotypes and Chemoresistance
by: Rahim N.S.; Wu Y.S.; Sim M.S.; Velaga A.; Bonam S.R.; Gopinath S.C.B.; Subramaniyan V.; Choy K.W.; Teow S.-Y.; Fareez I.M.; Samudi C.; Sekaran S.D.; Sekar M.; Guad R.M.
Published: (2023)

The pathway toward sustainable and resilient infrastructure development in Malaysia
by: Mustaffa N.K.; Shahrudin N.S.N.; Mustaffa A.
Published: (2023)