Anti-cancer potential of benzophenone-bis-Schiff bases on human pancreatic cancer cell line
Synthetic benzophenone-bis-Schiff bases (1-17) were evaluated for PC3 cell line inhibition. Most of the compounds showed cytotoxic effects but compounds 4, 8, 14, 16, and 17 were found to be potent. The growth inhibition of PC3 cells was in a concentration-dependent manner when treated with compound...
Published in: | Journal of the Chemical Society of Pakistan |
---|---|
Main Author: | Khan K.M.; Rasheed H.; Fatima B.; Hayat M.; Rahim F.; Ullah H.; Hameed A.; Taha M.; Tahir A.; Perveen S. |
Format: | Article |
Language: | English |
Published: |
Chemical Society of Pakistan
2016
|
Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84995460997&partnerID=40&md5=57fae9b20ad7f8219576edc21143ce65 |
Similar Items
-
Synthesis of benzophenone hydrazone analogs and their DPPH radical scavenging and urease inhibitory activities
by: Khan K.M.; Rahim F.; Khan A.; Ali S.; Taha M.; Saad S.M.; Khan M.; Najeebullah; Shaikh A.; Perveen S.; Choudhary M.I.
Published: (2015) -
Synthesis of symmetrical bis-Schiff base-disulfide hybrids as highly effective anti-leishmanial agents
by: Taha M.; Sain A.A.; Ali M.; Anouar E.H.; Rahim F.; Ismail N.H.; Adenan M.I.; Imran S.; Al-Harrasi A.; Nawaz F.; Iqbal N.; Khan K.M.
Published: (2020) -
Synthesis, in vitro thymidine phosphorylase inhibitory activity and molecular docking study of novel pyridine-derived bis-oxadiazole bearing bis-schiff base derivatives
by: Hussain R.; Rehman W.; Rahim F.; Khan S.; Alanazi A.S.; Alanazi M.M.; Rasheed L.; Khan Y.; Adnan. Ali. Shah S.; Taha M.
Published: (2023) -
Acylhydrazide schiff bases: Synthesis and antiglycation activity
by: Khan K.M.; Taha M.; Rahim F.; Fakhri M.I.; Jamil W.; Khan M.; Rasheed S.; Karim A.; Perveen S.; Choudhary M.I.
Published: (2013) -
The Roles of Immune Cells in Gastric Cancer: Anti-Cancer or Pro-Cancer?
by: Sukri A.; Hanafiah A.; Kosai N.R.
Published: (2022)