Ursodeoxycholic acid upregulates ERK and Akt in the protection of cardiomyocytes against CoCl2
Ursodeoxycholic acid (UDCA) is used to treat liver diseases and demonstrates cardioprotective effects. Accumulation of the plasma membrane sphingolipid sphingomyelin in the heart can lead to atherosclerosis and coronary artery disease. Sphingomyelinases (SMases) break down sphingomyelin, producing c...
發表在: | Genetics and Molecular Research |
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主要作者: | |
格式: | Article |
語言: | English |
出版: |
Fundacao de Pesquisas Cientificas de Ribeirao Preto
2016
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在線閱讀: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85011771016&doi=10.4238%2fgmr.15028150&partnerID=40&md5=b7f8089ab48055aece2c84d849640044 |