Hydrazinyl arylthiazole based pyridine scaffolds: Synthesis, structural characterization, in vitro α-glucosidase inhibitory activity, and in silico studies

Acarbose, miglitol, and voglibose are the inhibitors of α-glucosidase enzyme and being clinically used for the management of type-II diabetes mellitus. However, many adverse effects are also associated with them. So, the development of new therapeutic agents is an utmost interest in medicinal chemis...

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Bibliographic Details
Published in:European Journal of Medicinal Chemistry
Main Author: Ali F.; Khan K.M.; Salar U.; Taha M.; Ismail N.H.; Wadood A.; Riaz M.; Perveen S.
Format: Article
Language:English
Published: Elsevier Masson SAS 2017
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85021402072&doi=10.1016%2fj.ejmech.2017.06.041&partnerID=40&md5=cd545b4891f03d8f34b02880b9f5ff16