Synthesis of bis-indolylmethanes as new potential inhibitors of β-glucuronidase and their molecular docking studies

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Synthesis of bis-indolylmethanes as new potential inhibitors of β-glucuronidase and their molecular docking studies

Thirty-two (32) bis-indolylmethane-hydrazone hybrids 1–32 were synthesized and characterized by 1HNMR, 13CNNMR and HREI-MS. All compounds were evaluated in vitro for β-glucuronidase inhibitory potential. All analogs showed varying degree of β-glucuronidase inhibitory potential ranging from 0.10 ± 0....

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Bibliographic Details
Published in:	European Journal of Medicinal Chemistry
Main Author:	Taha M.; Ullah H.; Al Muqarrabun L.M.R.; Khan M.N.; Rahim F.; Ahmat N.; Ali M.; Perveen S.
Format:	Article
Language:	English
Published:	Elsevier Masson s.r.l. 2018
Online Access:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85033591574&doi=10.1016%2fj.ejmech.2017.10.071&partnerID=40&md5=25123fa8f7fff0f74d5ed0f20b7ab3da

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