Ternary copper(II) complex: NCI60 screening, toxicity studies, and evaluation of efficacy in xenograft models of nasopharyngeal carcinoma

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Ternary copper(II) complex: NCI60 screening, toxicity studies, and evaluation of efficacy in xenograft models of nasopharyngeal carcinoma

Copper(II) ternary complex, [Cu(phen)(C-dmg)(H2O)]NO3 was evaluated against a panel of cell lines, tested for in vivo efficacy in nasopharyngeal carcinoma xenograft models as well as for toxicity in NOD scid gamma mice. The Cu(II) complex displayed broad spectrum cytotoxicity against multiple cancer...

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Bibliographic Details
Published in:	PLoS ONE
Main Author:	Ahmad M.; Suhaimi S.-N.; Chu T.-L.; Aziz N.A.; Kornain N.-K.M.; Samiulla D.S.; Lo K.-W.; Ng C.-H.; Khoo A.S.-B.
Format:	Article
Language:	English
Published:	Public Library of Science 2018
Online Access:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85040468883&doi=10.1371%2fjournal.pone.0191295&partnerID=40&md5=789717f6362d34d10736bf5e91f94dc9

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