Evaluation of anti-lipase activity of leaf and bark extracts from aquilaria subintegra and A. Malaccensis

Obesity is one of the serious health condition in the world and contributes to many chronic illnesses augmenting to high risk of death rate. With the purpose of obesity treatment, natural sources come to be significant to replace commercial drugs due to their harmful effect to the body. Therefore, a...

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Published in:Marmara Pharmaceutical Journal
Main Author: Ibrahim M.; Syed Abdul Azziz S.S.; Wong C.F.; Wan Mohamad Din W.N.I.; Wan Mahamod W.R.; Bakri Y.M.; Ahmad M.S.; Yahaya R.; Ismail N.H.; Salleh W.M.N.H.W.
Format: Article
Language:English
Published: Marmara University 2018
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85041126839&doi=10.12991%2fmpj.2018.46&partnerID=40&md5=208e9b3d34455b89517d6d5e393aaff3
id 2-s2.0-85041126839
spelling 2-s2.0-85041126839
Ibrahim M.; Syed Abdul Azziz S.S.; Wong C.F.; Wan Mohamad Din W.N.I.; Wan Mahamod W.R.; Bakri Y.M.; Ahmad M.S.; Yahaya R.; Ismail N.H.; Salleh W.M.N.H.W.
Evaluation of anti-lipase activity of leaf and bark extracts from aquilaria subintegra and A. Malaccensis
2018
Marmara Pharmaceutical Journal
22
1
10.12991/mpj.2018.46
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85041126839&doi=10.12991%2fmpj.2018.46&partnerID=40&md5=208e9b3d34455b89517d6d5e393aaff3
Obesity is one of the serious health condition in the world and contributes to many chronic illnesses augmenting to high risk of death rate. With the purpose of obesity treatment, natural sources come to be significant to replace commercial drugs due to their harmful effect to the body. Therefore, a lot of studies were conducted on natural sources due to their potential as medicinal herbs. Aquilaria sp. plants are well known in traditional medicine as a sedative, analgesic and digestive. Even though there were no reports on applications of Aquilaria sp. towards obesity treatment, this plant has traditionally been used as laxative for weight reducing. In this study, the anti-lipase activity of an extract of barks and leaves from A. subintegra and A. malaccensis were investigated. The anti-lipase activity was measured by colorimetric assay on pancreatic lipase activity using porcine pancreatic lipase (PPL; triacylglycerol lipase, EC 3.1.1.3). The result indicated that among these two species of Aquilaria, A. malaccensis bark in dichloromethane crude showed high anti-lipase activity. Thus, these results suggest that Aquilaria sp. plant extracts might be of therapeutic interest with respect to the treatment. © 2017 Marmara University Press, All Rights Reserved.
Marmara University
13090801
English
Article
All Open Access; Gold Open Access
author Ibrahim M.; Syed Abdul Azziz S.S.; Wong C.F.; Wan Mohamad Din W.N.I.; Wan Mahamod W.R.; Bakri Y.M.; Ahmad M.S.; Yahaya R.; Ismail N.H.; Salleh W.M.N.H.W.
spellingShingle Ibrahim M.; Syed Abdul Azziz S.S.; Wong C.F.; Wan Mohamad Din W.N.I.; Wan Mahamod W.R.; Bakri Y.M.; Ahmad M.S.; Yahaya R.; Ismail N.H.; Salleh W.M.N.H.W.
Evaluation of anti-lipase activity of leaf and bark extracts from aquilaria subintegra and A. Malaccensis
author_facet Ibrahim M.; Syed Abdul Azziz S.S.; Wong C.F.; Wan Mohamad Din W.N.I.; Wan Mahamod W.R.; Bakri Y.M.; Ahmad M.S.; Yahaya R.; Ismail N.H.; Salleh W.M.N.H.W.
author_sort Ibrahim M.; Syed Abdul Azziz S.S.; Wong C.F.; Wan Mohamad Din W.N.I.; Wan Mahamod W.R.; Bakri Y.M.; Ahmad M.S.; Yahaya R.; Ismail N.H.; Salleh W.M.N.H.W.
title Evaluation of anti-lipase activity of leaf and bark extracts from aquilaria subintegra and A. Malaccensis
title_short Evaluation of anti-lipase activity of leaf and bark extracts from aquilaria subintegra and A. Malaccensis
title_full Evaluation of anti-lipase activity of leaf and bark extracts from aquilaria subintegra and A. Malaccensis
title_fullStr Evaluation of anti-lipase activity of leaf and bark extracts from aquilaria subintegra and A. Malaccensis
title_full_unstemmed Evaluation of anti-lipase activity of leaf and bark extracts from aquilaria subintegra and A. Malaccensis
title_sort Evaluation of anti-lipase activity of leaf and bark extracts from aquilaria subintegra and A. Malaccensis
publishDate 2018
container_title Marmara Pharmaceutical Journal
container_volume 22
container_issue 1
doi_str_mv 10.12991/mpj.2018.46
url https://www.scopus.com/inward/record.uri?eid=2-s2.0-85041126839&doi=10.12991%2fmpj.2018.46&partnerID=40&md5=208e9b3d34455b89517d6d5e393aaff3
description Obesity is one of the serious health condition in the world and contributes to many chronic illnesses augmenting to high risk of death rate. With the purpose of obesity treatment, natural sources come to be significant to replace commercial drugs due to their harmful effect to the body. Therefore, a lot of studies were conducted on natural sources due to their potential as medicinal herbs. Aquilaria sp. plants are well known in traditional medicine as a sedative, analgesic and digestive. Even though there were no reports on applications of Aquilaria sp. towards obesity treatment, this plant has traditionally been used as laxative for weight reducing. In this study, the anti-lipase activity of an extract of barks and leaves from A. subintegra and A. malaccensis were investigated. The anti-lipase activity was measured by colorimetric assay on pancreatic lipase activity using porcine pancreatic lipase (PPL; triacylglycerol lipase, EC 3.1.1.3). The result indicated that among these two species of Aquilaria, A. malaccensis bark in dichloromethane crude showed high anti-lipase activity. Thus, these results suggest that Aquilaria sp. plant extracts might be of therapeutic interest with respect to the treatment. © 2017 Marmara University Press, All Rights Reserved.
publisher Marmara University
issn 13090801
language English
format Article
accesstype All Open Access; Gold Open Access
record_format scopus
collection Scopus
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