| Summary: | Pithecellobium jiringa (P. jiringa) is economically important due to its various traditional uses in treating hypertension and diabetes (seeds), medicine (leaves) and source of dye for silk (pods). This is a pioneer study that reports its effectiveness as antimicrobial agent from stem bark of P. jiringa. The present study was carried out to detect preliminary phytochemicals and antimicrobial of solvent extracts from P. jiringa stem bark. Qualitative phytochemical analysis was performed on ethanol and ethyl acetate extracts. These extracts were investigated for their antimicrobial activity of different microorganism tests including bacteria and fungi by using agar disc diffusion technique. Tannins, flavonoids, terpenoids and saponins were the main metabolites found in phytochemical screenings. Both ethanol and ethyl acetate extracts exhibited marked antimicrobial activity against skin disease caused-microbes Staphylococcus aureus, Staphylococcus epidermidis and Trychophyton mentagrophytes with highest inhibition zone (IZ) of 23 mm at 200 mg/mL ethyl acetate extracts. The current study confirmed that the stem bark of P. jiringa has a potential source of active antimicrobial agent. Further analysis on the isolation and characterization of compound form P. jiringa stem bark, responsible for antimicrobial properties is in progress. © 2018, Malaysian Society of Analytical Sciences. All rights reserved.
|
|---|