Antinociceptive activity of petroleum ether fraction obtained from methanolic extract of Clinacanthus nutans leaves involves the activation of opioid receptors and NO-mediated/cGMP-independent pathway
Background: Methanol extract (MECN) of Clinacanthus nutans Lindau leaves (family Acanthaceae) demonstrated peripherally and centrally mediated antinociceptive activity via the modulation of opioid/NO-mediated, but cGMP-independent pathway. In the present study, MECN was sequentially partitioned to o...
Published in: | BMC Complementary and Alternative Medicine |
---|---|
Main Author: | Zakaria Z.A.; Abdul Rahim M.H.; Mohd Sani M.H.; Omar M.H.; Ching S.M.; Abdul Kadir A.; Ahmed Q.U. |
Format: | Article |
Language: | English |
Published: |
BioMed Central Ltd.
2019
|
Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85063801773&doi=10.1186%2fs12906-019-2486-8&partnerID=40&md5=d764576ae88c4afaa14f48f97f914a43 |
Similar Items
-
Methanolic extract of clinacanthus nutans exerts antinociceptive activity via the opioid/nitric oxide-mediated, but cGMP-independent, pathways
by: Abdul Rahim M.H.; Zakaria Z.A.; Mohd Sani M.H.; Omar M.H.; Yakob Y.; Cheema M.S.; Ching S.M.; Ahmad Z.; Abdul Kadir A.
Published: (2016) -
Antinociceptive Activity of Petroleum Ether Fraction of Clinacanthus nutans Leaves Methanolic Extract: Roles of Nonopioid Pain Modulatory Systems and Potassium Channels
by: Zakaria Z.A.; Abdul Rahim M.H.; Roosli R.A.J.; Mohd Sani M.H.; Marmaya N.H.; Omar M.H.; Teh L.K.; Salleh M.Z.
Published: (2019) -
Antinociceptive Activity of Methanolic Extract of Clinacanthus nutans Leaves: Possible Mechanisms of Action Involved
by: Zakaria Z.A.; Abdul Rahim M.H.; Roosli R.A.J.; Mohd Sani M.H.; Omar M.H.; Tohid S.F.; Othman F.; Ching S.M.; Abdul Kadir A.
Published: (2018) -
Antinociception of petroleum ether fraction derived from crude methanol extract of Melastoma malabathricum leaves and its possible mechanisms of action in animal models
by: Zakaria Z.A.; Jaios E.S.; Omar M.H.; Abd. Rahman S.; Hamid S.S.A.; Ching S.M.; Teh L.K.; Salleh M.Z.; Deny S.; Taher M.
Published: (2016) -
Acute and sub-chronic oral toxicity studies of methanol extract of clinacanthus nutans in mice
by: Zakaria Z.A.; Rahim M.H.A.; Mohtarrudin N.; Kadir A.A.; Cheema M.S.; Ahmad Z.; Mooi C.S.; Tohid S.F.M.
Published: (2016)