Synthesis and Nucleotide Pyrophosphatase/Phosphodiesterase Inhibition Studies of Carbohydrazides Based on Benzimidazole-Benzothiazine Skeleton
Ecto-nucleotide pyrophosphatases/phosphodiesterases (ENPPs) are important family of ecto-nucleotidases. There are seven members of ENPP family out of which ENPP1 and ENPP3 hydrolyze nucleotides whereas, ENPP2 preferably hydrolyzes phospholipids as compared to nucleotides. Overexpression of ENPP1 and...
Published in: | ChemistrySelect |
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Main Author: | |
Format: | Article |
Language: | English |
Published: |
Wiley-Blackwell
2020
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Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85097212373&doi=10.1002%2fslct.202003479&partnerID=40&md5=544cdecf3764b61111c6ba1dc8a8ddc1 |