Synthesis and Nucleotide Pyrophosphatase/Phosphodiesterase Inhibition Studies of Carbohydrazides Based on Benzimidazole-Benzothiazine Skeleton

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Synthesis and Nucleotide Pyrophosphatase/Phosphodiesterase Inhibition Studies of Carbohydrazides Based on Benzimidazole-Benzothiazine Skeleton

Ecto-nucleotide pyrophosphatases/phosphodiesterases (ENPPs) are important family of ecto-nucleotidases. There are seven members of ENPP family out of which ENPP1 and ENPP3 hydrolyze nucleotides whereas, ENPP2 preferably hydrolyzes phospholipids as compared to nucleotides. Overexpression of ENPP1 and...

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Bibliographic Details
Published in:	ChemistrySelect
Main Author:	Kanwal A.; Ullah S.; Ahmad M.; Pelletier J.; Aslam S.; Sultan S.; Sévigny J.; Iqbal M.; Iqbal J.
Format:	Article
Language:	English
Published:	Wiley-Blackwell 2020
Online Access:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85097212373&doi=10.1002%2fslct.202003479&partnerID=40&md5=544cdecf3764b61111c6ba1dc8a8ddc1

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