Role of ErbB1 in the Underlying Mechanism of Lapatinib-Induced Diarrhoea: A Review

Lapatinib, an orally administered small-molecule tyrosine kinase inhibitor (SM-TKI), is an effective treatment for ErbB2-positive breast cancer. However, its efficacy as one of the targeted cancer therapies has been hampered by several adverse effects, especially gastrointestinal toxicity, commonly...

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Bibliographic Details
Published in:BioMed Research International
Main Author: Raja Sharin R.N.F.S.; Khan J.; Ibahim M.J.; Muhamad M.; Bowen J.; Mohamad Zain W.N.I.W.
Format: Review
Language:English
Published: Hindawi Limited 2022
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85133610403&doi=10.1155%2f2022%2f4165808&partnerID=40&md5=b2db8a2d05dc4eac4e5b45cdad0fbdb5