Exploring Novel Pyridine Carboxamide Derivatives as Urease Inhibitors: Synthesis, Molecular Docking, Kinetic Studies and ADME Profile
The rapid development of resistance by ureolytic bacteria which are involved in various life-threatening conditions such as gastric and duodenal cancer has induced the need to develop a new line of therapy which has anti-urease activity. A series of pyridine carboxamide and carbothioamide derivative...
| Published in: | Pharmaceuticals |
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| Main Author: | |
| Format: | Article |
| Language: | English |
| Published: |
MDPI
2022
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| Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85140925076&doi=10.3390%2fph15101288&partnerID=40&md5=0f1a2f0c2a4e1cbca7be102f22639198 |