Drug-related problems among older people with dementia: A systematic review
Introduction: Dementia is a disorder that causes a decline of cognitive function, and it affects millions of people worldwide. Increased availability of medications used to treat dementia will inevitably increase the likelihood of drug-related problems (DRPs). Objective: This systematic review sough...
Published in: | Research in Social and Administrative Pharmacy |
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Elsevier Inc.
2023
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2-s2.0-85150381729 Xue Qin Q.N.; Ming L.C.; Abd Wahab M.S.; Tan C.S.; Yuda A.; Hermansyah A. Drug-related problems among older people with dementia: A systematic review 2023 Research in Social and Administrative Pharmacy 19 6 10.1016/j.sapharm.2023.02.015 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85150381729&doi=10.1016%2fj.sapharm.2023.02.015&partnerID=40&md5=efbebe2379225186c136b1c22f7548db Introduction: Dementia is a disorder that causes a decline of cognitive function, and it affects millions of people worldwide. Increased availability of medications used to treat dementia will inevitably increase the likelihood of drug-related problems (DRPs). Objective: This systematic review sought to identify DRPs due to medication misadventures, including adverse drug reactions (ADRs), and use of inappropriate medications, among patients with dementia or cognitive impairments. Methods: The included studies were retrieved from the electronic databases PubMed and SCOPUS, and a preprint platform (MedRXiv) which were searched from their inception through August 2022. The English-language publications that reported DRPs among dementia patients were included. The JBI Critical Appraisal Tool for quality assessment was used to evaluate the quality of studies included in the review. Results: Overall, 746 distinct articles were identified. Fifteen studies met the inclusion criteria and reported the most common DRPs, which comprised medication misadventures (n = 9), such as ADRs, inappropriate prescription use, and potentially inappropriate medication use (n = 6). Conclusion: This systematic review provides evidence that DRPs are prevalent among dementia patients, particularly the older people. It indicates that medication misadventures such as ADRs and inappropriate drug use, as well as potentially inappropriate medications, are the most prevalent DRPs among older people with dementia. Due to the small number of included studies, however, additional studies are required to improve comprehension about the issue. © 2023 Elsevier Inc. Elsevier Inc. 15517411 English Review All Open Access; Green Open Access |
author |
Xue Qin Q.N.; Ming L.C.; Abd Wahab M.S.; Tan C.S.; Yuda A.; Hermansyah A. |
spellingShingle |
Xue Qin Q.N.; Ming L.C.; Abd Wahab M.S.; Tan C.S.; Yuda A.; Hermansyah A. Drug-related problems among older people with dementia: A systematic review |
author_facet |
Xue Qin Q.N.; Ming L.C.; Abd Wahab M.S.; Tan C.S.; Yuda A.; Hermansyah A. |
author_sort |
Xue Qin Q.N.; Ming L.C.; Abd Wahab M.S.; Tan C.S.; Yuda A.; Hermansyah A. |
title |
Drug-related problems among older people with dementia: A systematic review |
title_short |
Drug-related problems among older people with dementia: A systematic review |
title_full |
Drug-related problems among older people with dementia: A systematic review |
title_fullStr |
Drug-related problems among older people with dementia: A systematic review |
title_full_unstemmed |
Drug-related problems among older people with dementia: A systematic review |
title_sort |
Drug-related problems among older people with dementia: A systematic review |
publishDate |
2023 |
container_title |
Research in Social and Administrative Pharmacy |
container_volume |
19 |
container_issue |
6 |
doi_str_mv |
10.1016/j.sapharm.2023.02.015 |
url |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85150381729&doi=10.1016%2fj.sapharm.2023.02.015&partnerID=40&md5=efbebe2379225186c136b1c22f7548db |
description |
Introduction: Dementia is a disorder that causes a decline of cognitive function, and it affects millions of people worldwide. Increased availability of medications used to treat dementia will inevitably increase the likelihood of drug-related problems (DRPs). Objective: This systematic review sought to identify DRPs due to medication misadventures, including adverse drug reactions (ADRs), and use of inappropriate medications, among patients with dementia or cognitive impairments. Methods: The included studies were retrieved from the electronic databases PubMed and SCOPUS, and a preprint platform (MedRXiv) which were searched from their inception through August 2022. The English-language publications that reported DRPs among dementia patients were included. The JBI Critical Appraisal Tool for quality assessment was used to evaluate the quality of studies included in the review. Results: Overall, 746 distinct articles were identified. Fifteen studies met the inclusion criteria and reported the most common DRPs, which comprised medication misadventures (n = 9), such as ADRs, inappropriate prescription use, and potentially inappropriate medication use (n = 6). Conclusion: This systematic review provides evidence that DRPs are prevalent among dementia patients, particularly the older people. It indicates that medication misadventures such as ADRs and inappropriate drug use, as well as potentially inappropriate medications, are the most prevalent DRPs among older people with dementia. Due to the small number of included studies, however, additional studies are required to improve comprehension about the issue. © 2023 Elsevier Inc. |
publisher |
Elsevier Inc. |
issn |
15517411 |
language |
English |
format |
Review |
accesstype |
All Open Access; Green Open Access |
record_format |
scopus |
collection |
Scopus |
_version_ |
1809678017461485568 |