Development and Evaluation of a High-Performance Electrochemical Potentiostat-Based Desktop Application for Rapid SARS-CoV-2 Testing

• Published in: Indonesian Journal of Electrical Engineering and Informatics
• Main Author: Assaig F.A.; Gunawan T.S.; Nordin A.N.; Rahim R.Ab.; Zain Z.M.; Zain R.M.; Arifin F.
• Format: Article
• Language: English
• Published: Institute of Advanced Engineering and Science 2023
• Online Access: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85170085587&doi=10.52549%2fijeei.v11i2.4645&partnerID=40&md5=1155f1f17a88c88f33535f7da0e63e10

The COVID-19 pandemic has necessitated the development of rapid and trustworthy diagnostic tools. Reverse transcription-polymerase chain reaction (RT-PCR) is the gold standard for detecting SARS-CoV-2 but has cost and time constraints. The sensitivity, specificity, and low cost of electrochemical biosensors make them an attractive alternative for virus detection. This study aims to develop and evaluate a high-performance desktop application for an electrochemical potentiostat-based SARS-CoV-2 test device, with a user-friendly interface that automatically interprets results, to expedite the testing process and improve accessibility, particularly in resource-limited settings. The application was built with the Electron framework and the HTML, CSS, and JavaScript programming languages. Our findings indicate that the developed electrochemical potentiostat-based desktop application demonstrates high accuracy compared to commercial software, achieving rapid detection within 30 seconds. The graphical user interface was found to be straightforward and user-friendly, requiring minimal training for efficient system operation. Our electrochemical potentiostat-based desktop application represents a valuable tool for rapid SARS-CoV-2 testing, particularly in settings with limited resources. This research contributes to developing rapid and reliable diagnostic tools for SARS-CoV-2 and potentially other pandemic-causing viruses, addressing the pressing need for improved public health surveillance and response strategies. © 2023 Institute of Advanced Engineering and Science. All rights reserved.