The potential of carbonic anhydrase enzymes as a novel target for anti-cancer treatment
Carbonic anhydrase (CA) is a zinc-dependent metal enzyme that maintains the pH and carbon dioxide (CO2) homeostasis in cells by catalyzing the reversible hydration and dehydration of CO2 and bicarbonate (HCO3−). In mammals, there are 16 isozymes of CA existed, namely CAI to CAXIV, but only 15 isozym...
| Published in: | European Journal of Pharmacology |
|---|---|
| Main Author: | |
| Format: | Review |
| Language: | English |
| Published: |
Elsevier B.V.
2024
|
| Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85194878339&doi=10.1016%2fj.ejphar.2024.176677&partnerID=40&md5=79c8fee42d777f4918cdf2e1b80fab16 |