In silico and in vivo evaluations of fisetin and fisetin-loaded nanosuspension on monoamine oxidase inhibition in Aβ(25–35) induced dementia in mice model

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In silico and in vivo evaluations of fisetin and fisetin-loaded nanosuspension on monoamine oxidase inhibition in Aβ(25–35) induced dementia in mice model

Background: Amyloid beta (Aβ) plaques on the extracellular matrix and intracellular neurofibrillary tangles comprise the key indicative pathology of Alzheimer's disease (AD). Fisetin, an antioxidant bioactive compound having pharmacotherapeutic effects is applied by traditional Chinese medicine...

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Bibliographic Details
Published in:	Pharmacological Research - Modern Chinese Medicine
Main Author:	Zolkiffly S.Z.I.; Hazizul Hasan M.; Jusoh S.A.; Janakiraman A.K.; Sukumaran S.K.; Husain N.; Zakaria Y.; Jayasingh Chellammal H.S.
Format:	Article
Language:	English
Published:	Elsevier B.V. 2024
Online Access:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85209114940&doi=10.1016%2fj.prmcm.2024.100547&partnerID=40&md5=fbd3361f2709736858ecf88c6de9df69

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