The Effects of Different Solubilizing Agents on the Transport and Pharmacokinetic Profiles of Indomethacin: in vitro and in vivo Approach; [Kesan Agen Pelarut Berbeza Terhadap Profil Pengangkutan dan Farmakokinetik Indometasin: Pendekatan in vitro dan in vivo]
The poor water solubility of new chemical entities (NCEs) discovered in pharmaceutical screening programs hampers their development and limits effective treatment delivery. Solubilizing agents offer a direct approach to increase solubility and oral bioavailability. This study employed indomethacin a...
Published in: | Sains Malaysiana |
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Main Author: | Zainuddin S.A.; Hamid A.L.A.B.; Rafandi A.I.; Mohamad M.; Hamid K.A.; Khalid S.H. |
Format: | Article |
Language: | English |
Published: |
Penerbit Universiti Kebangsaan Malaysia
2024
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Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85211007929&doi=10.17576%2fjsm-2024-5311-17&partnerID=40&md5=844528476b4ffc4f210086a8a2485019 |
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