Trabecular meshwork ECM remodeling in glaucoma: could RAS be a target?

Introduction: Disturbances of extracellular matrix (ECM) homeostasis in trabecular meshwork (TM) cause increased aqueous outflow resistance leading to elevated intraocular pressure (IOP) in glaucomatous eyes. Therefore, restoration of ECM homeostasis is a rational approach to prevent disease progres...

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Bibliographic Details
Published in:Expert Opinion on Therapeutic Targets
Main Author: 2-s2.0-85049096441
Format: Review
Language:English
Published: Taylor and Francis Ltd 2018
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85049096441&doi=10.1080%2f14728222.2018.1486822&partnerID=40&md5=64f55f1df48cbd095a93ff671a3e32f2