New class of acetylcholinesterase inhibitors from the stem bark of Knema laurina and their structural insights

Bioassay-guided extraction of the stem bark of Knema laurina showed the acetylcholinesterase (AChE) inhibitory activity of DCM and hexane fractions. Further repeated column chromatography of hexane and DCM fractions resulted in the isolation and purification of five alkenyl phenol and salicylic acid...

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Bibliographic Details
Published in:Bioorganic and Medicinal Chemistry Letters
Main Author: 2-s2.0-79958793776
Format: Article
Language:English
Published: 2011
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-79958793776&doi=10.1016%2fj.bmcl.2011.04.065&partnerID=40&md5=171a1a7a360780d4fcf6a84eb9a65a80