Synthesis, Spectral Evaluation and in Silico Studies of S-Aralkylated 5-(4-methoxyphenyl)-4-phenyl-4H-1,2,4-triazole-3-thiols: As suitable Alzheimer's disease drug candidates
Our efforts lay emphasis on synthesis of S-aralkylated 5-(4-OMeC6H5)-4-phenyl-4H-1,2,4-triazol-3-thiols like pharmacologically active candidates to counter neurodegenerative disorder; Alzheimer's disease. A synthetic strategy was instigated by esterifying 4-methoxybenzoic acid through Fisher es...
الحاوية / القاعدة: | Journal of the Chemical Society of Pakistan |
---|---|
المؤلف الرئيسي: | 2-s2.0-85121793476 |
التنسيق: | مقال |
اللغة: | English |
منشور في: |
Chemical Society of Pakistan
2021
|
الوصول للمادة أونلاين: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85121793476&partnerID=40&md5=9027443cdbef722c5b199131781f8116 |
مواد مشابهة
-
S-substituted derivatives of 1,2,4-triazol-3-thiol as new drug candidates for type II diabetes
بواسطة: 2-s2.0-85047939044
منشور في: (2018) -
Design, synthesis of triazole-based scaffolds, N-(substitutedphenyl)-2-(5-(4-methoxyphenyl)-4-phenyl-4H-1,2,4-triazol-3-ylthiol)acetamides: As potential anti-cholinesterase agents for neurodegenerative diseases
بواسطة: 2-s2.0-85160806262
منشور في: (2023) -
Discovery of Dual Inhibitors of Acetyl and Butrylcholinesterase and Antiproliferative Activity of 1,2,4-Triazole-3-thiol: Synthesis and In Silico Molecular Study
بواسطة: 2-s2.0-85087042710
منشور في: (2020) -
Synthesis, enzyme inhibitory kinetics, & computational studies of N-(substituted phenyl)-(5-(3,4-dichlorobenzyl)-4-(4-chlorophenyl)-4H-1,2,4-triazol-3-ylthio)methylbenzamides: As potent alkaline phosphatase inhibitors
بواسطة: 2-s2.0-85204404556
منشور في: (2025) -
Synthesis, biological evaluation, and molecular docking study of novel 1,2,4-substituted triazoles as inhibitors of alzheimer’s disease
بواسطة: 2-s2.0-85136203736
منشور في: (2022)