Synthesis of novel N-(1,3-thiazol-2-yl)benzamide clubbed oxadiazole scaffolds: Urease inhibition, Lipinski rule and molecular docking analyses

Present work aimed to synthesize some unique bi-heterocyclic benzamides as lead compounds for the in vitro inhibition of urease enzyme, followed by in silico studies. These targeted benzamides were synthesized in good yields through a multi-step protocol and their struct...

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发表在:Bioorganic Chemistry
主要作者: 2-s2.0-85054810473
格式: 文件
语言:English
出版: Academic Press Inc. 2019
在线阅读:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85054810473&doi=10.1016%2fj.bioorg.2018.10.018&partnerID=40&md5=5ed095fef911fb73da03a549a6c3c914