Composition of overlapping protein-protein and protein-ligand interfaces

Protein-protein interactions (PPIs) play a major role in many biological processes and they represent an important class of targets for therapeutic intervention. However, targeting PPIs is challenging because often no convenient natural substrates are available as starting point for small-molecule d...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:PLoS ONE
المؤلف الرئيسي: 2-s2.0-84951058673
التنسيق: مقال
اللغة:English
منشور في: Public Library of Science 2015
الوصول للمادة أونلاين:https://www.scopus.com/inward/record.uri?eid=2-s2.0-84951058673&doi=10.1371%2fjournal.pone.0140965&partnerID=40&md5=463f13dd2ce87ea8b8e07a5a9a47a250