Synthesis, biological evaluation, molecular docking and dynamic simulation of novel benzofuran derivatives as potential agents against Alzheimer's disease

We have synthesized novel benzofuran derivatives (1–20), characterized through different spectroscopic techniques such as 1HNMR, 13CNMR, HREI-MS and screened against acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) enzymes. All derivatives showed inhibitory activities having IC50 values...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:Journal of Molecular Structure
المؤلف الرئيسي: 2-s2.0-85206074124
التنسيق: مقال
اللغة:English
منشور في: Elsevier B.V. 2025
الوصول للمادة أونلاين:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85206074124&doi=10.1016%2fj.molstruc.2024.140279&partnerID=40&md5=e40ae289255301808cdeec9a7a82529e