Development of bis-thiobarbiturates as successful urease inhibitors and their molecular modeling studies
Bis-thiobarbiturate derivatives 1-15 have been synthesized, characterized by 1HNMR and EI-MS and screened for urease inhibition. All compounds showed various degree of urease inhibitory activity with IC50 values ranging 7.45 ± 0.12 - 74.24 ± 0.81 μmol/L while the standard thiourea behaved normally (...
| الحاوية / القاعدة: | Chinese Chemical Letters |
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| المؤلف الرئيسي: | |
| التنسيق: | مقال |
| اللغة: | English |
| منشور في: |
Elsevier
2016
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| الوصول للمادة أونلاين: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84960192729&doi=10.1016%2fj.cclet.2015.12.035&partnerID=40&md5=811cfe660bde2a5cdcd83e2b4571e983 |