2-(2′-Pyridyl) benzimidazole derivatives and their urease inhibitory activity
Pyridyl-benzimidazole analogues 1-11 with variable substituent on phenyl ring of phenacyl moiety were synthesized and evaluated for their urease inhibitory activity. The compounds exhibited urease inhibition with IC50 between 19.22 and 77.31 μM. Compounds 4 (IC50 = 19.22 ± 0.49 μM) showed a urease i...
| 發表在: | Medicinal Chemistry Research |
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| 主要作者: | |
| 格式: | Article |
| 語言: | English |
| 出版: |
Birkhauser Boston
2014
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| 在線閱讀: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85027926278&doi=10.1007%2fs00044-014-1015-z&partnerID=40&md5=f027f7827a6f2f83909d4abaca7b6184 |