Synthesis and novel structural hybrid analogs of oxindole derivatives bearing piperidine ring, their antidiabetics II activity and molecular docking study

QR Code

Synthesis and novel structural hybrid analogs of oxindole derivatives bearing piperidine ring, their antidiabetics II activity and molecular docking study

Synthesis of new potent antidiabetic scaffolds have grabbed the attention of researchers worldwide. In this context, new oxindole bearing piperidine derivatives (1-18) were synthesized and characterized using 1 HNMR, 13CNMR, and EI-MS, and then tested their potency as alpha-glucosidase and alpha-amy...

書目詳細資料
發表在:	JOURNAL OF MOLECULAR STRUCTURE
Main Authors:	Mukhliss, Layan; Taha, Muhammad; Rahim, Fazal; Adalat, Bushra; Ajmal, Amar; Wadood, Abdul; Uddin, Nizam; Khan, Khalid Mohammed; Shah, Syed Adnan Ali
格式:	Article
語言:	English
出版:	ELSEVIER 2025
主題:	Chemistry
在線閱讀:	https://www-webofscience-com.uitm.idm.oclc.org/wos/woscc/full-record/WOS:001426238300001

相似書籍

Synthesis and novel structural hybrid analogs of oxindole derivatives bearing piperidine ring, their antidiabetics II activity and molecular docking study
由: Mukhliss L.; Taha M.; Rahim F.; Adalat B.; Ajmal A.; Wadood A.; Uddin N.; Khan K.M.; Ali Shah S.A.
出版: (2025)

Synthesis and novel structural hybrid analogs of oxindole derivatives bearing piperidine ring, their antidiabetics II activity and molecular docking study
由: 2-s2.0-85217236617
出版: (2025)

Identification of Potent Inhibitors of Alzheimer's Disease Based on Benzodioxin-Thiosemicarbazide Analogues and Molecular Docking Study
由: Taha, et al.
出版: (2025)

Synthesis of piperazine sulfonamide analogs as diabetic-II inhibitors and their molecular docking study
由: 2-s2.0-85032929001
出版: (2017)

Antioxidant and antidiabetic potential of Malaysian Uncaria
由: 2-s2.0-79958815926
出版: (2011)

Synthesis, α-glucosidase inhibitory activity and in silico study of tris-indole hybrid scaffold with oxadiazole ring: As potential leads for the management of type-II diabetes mellitus
由: 2-s2.0-85025127822
出版: (2017)

Synthesis and Molecular Docking Studies of Novel Biheterocyclic Propanamides as Antidiabetic Agents Having Mild Cytotoxicity
由: 2-s2.0-85163537561
出版: (2023)

Synthesis of oxadiazole-coupled-thiadiazole derivatives as a potent β-glucuronidase inhibitors and their molecular docking study
由: Taha M.; Imran S.; Alomari M.; Rahim F.; Wadood A.; Mosaddik A.; Uddin N.; Gollapalli M.; Alqahtani M.A.; Bamarouf Y.A.
出版: (2019)

Ring vaccination for monkeypox containment: Strategic implementation and challenges
由: Choudhary O.P.; Priyanka; Fahrni M.L.; Saied A.A.; Chopra H.
出版: (2022)

Influence of membrane character on suppression of coffee-ring effect
由: Shahruddin S.S.; Ideris N.; Abu Bakar N.F.; Ahmad A.L.; Lah N.F.C.
出版: (2020)

Ring vaccination for monkeypox containment: Strategic implementation and challenges
由: 2-s2.0-85137081712
出版: (2022)

Synthesis of new antibacterial agents encompassing tosyl, piperidine, propanamide and 1,3,4-oxadiazole functionalities
由: 2-s2.0-85090136596
出版: (2020)

Suppression of Coffee-Ring Effect on Nitrocellulose Membrane: Effect of Polyethylene Glycol
由: Shahruddin S.S.; Ideris N.; Kamarulzaman N.A.
出版: (2022)

Forgotten Topological Index of The Zero Divisor Graph for Some Rings of Integers
由: Ismail, et al.
出版: (2025)

Forgotten Topological Index of The Zero Divisor Graph for Some Rings of Integers
由: 2-s2.0-86000452054
出版: (2025)

Synthesis, multiparametric structure assessment and biological evaluation of some new 1,3,4-oxadiazoles containing piperidine nucleus
由: 2-s2.0-85025480907
出版: (2017)

Hybrid benzothiazole analogs as antiurease agent: Synthesis and molecular docking studies
由: 2-s2.0-84962360234
出版: (2016)

2-(2'-pyridyl) benzimidazole analogs and their ß-glucuronidase inhibitory activity
由: 2-s2.0-84953331043
出版: (2015)

Dithiocarbazate Ligand-Based Cu(II), Ni(II), and Zn(II) Complexes: Synthesis, Structural Investigations, Cytotoxicity, DNA Binding, and Molecular Docking Studies
由: 2-s2.0-85135689592
出版: (2022)

Enhanced Zn(II) and Pb(II) removal from wastewater using thiolated chitosan beads (ETB); [Peningkatan jerapan Zn(II) dan Pb(II) daripada sisa air dengan manik kitosan tertiol]
由: Yong S.K.; Bolan N.; Lombi E.; Skinner W.
出版: (2015)

Synthesis, In Vitro Biological Evaluation and Molecular Modeling of Benzimidazole-Based Pyrrole/Piperidine Hybrids Derivatives as Potential Anti-Alzheimer Agents
由: 2-s2.0-85191352219
出版: (2024)

Sierpinski Gasket fractal antenna with ring-shape defected ground structure for RFID application
由: 2-s2.0-84922803343
出版: (2015)

Analytical Separation Method: A Student’s Perception on Analogy-based Teaching for Terminology
由: 2-s2.0-85128803888
出版: (2022)

Synthesis and characterization of thiolated chitosan beads for removal of Cu(II) and Cd(II) from wastewater
由: Yong S.K.; Bolan N.; Lombi E.; Skinner W.
出版: (2013)

Synthesis, biological and computational evaluation of benzoxazole hybrid analogs as potential anti-Alzheimer's agents
由: 2-s2.0-85204151475
出版: (2024)

Synthesis of benzimidazole–based analogs as anti alzheimer’s disease compounds and their molecular docking studies
由: 2-s2.0-85093694209
出版: (2020)

Synthesis of chromen-4-one-oxadiazole substituted analogs as potent β-glucuronidase inhibitors
由: 2-s2.0-85064857181
出版: (2019)

Synthesis, in vitro α-glucosidase inhibitory potential and molecular docking study of thiadiazole analogs
由: 2-s2.0-85044438335
出版: (2018)

Synthesis, structural elucidation, Hirshfeld surface analysis and cytotoxicity studies of homometallic dinuclear Cu(II), Ni(II) and Zn(II) Schiff base complexes derived from m-phenylenediamine
由: 2-s2.0-85172419958
出版: (2023)

Investigating CO2 storage properties of Pd(II) and Co(II) chelates of a Schiff's base ligand
由: Ahmed A.J.; Alias M.; Ahmed D.S.; Abdallh M.; Bufaroosha M.; Jawad A.H.; Yousif E.
出版: (2023)

Investigating CO2 storage properties of Pd(II) and Co(II) chelates of a Schiff's base ligand
由: 2-s2.0-85152445338
出版: (2023)

Benzoxazole based thiazole hybrid analogs: Synthesis, in vitro cholinesterase inhibition, and molecular docking studies
由: 2-s2.0-85145589794
出版: (2023)

Synthesis, structural characterization, and catalytic performance of Pd(II) complexes with fluorine- and methyl-substituted Schiff bases: Experimental and theoretical insights
由: Nasaruddin, et al.
出版: (2025)

The β-carboline analogs as a potent inhibitor for Alzheimer's Disease, molecular docking and dynamics simulation study
由: 2-s2.0-85173583185
出版: (2023)

Synthesis, molecular docking, acetylcholinesterase and butyrylcholinesterase inhibitory potential of thiazole analogs as new inhibitors for Alzheimer disease
由: 2-s2.0-84940020718
出版: (2015)

Penile strangulation as a consequence of autoerection with polyvinyl chloride plastic pipe ring: A case report and method of treatment
由: Baharudin N.N.; Zahar N.S.; Zainal Abidin Z.A.
出版: (2018)

Penile strangulation as a consequence of autoerection with polyvinyl chloride plastic pipe ring: A case report and method of treatment
由: 2-s2.0-85052961507
出版: (2018)

Production of activated carbon from coal with H3PO4 activation for adsorption of Fe(II) and Mn(II) in acid mine drainage
由: Suliestyah; Tuheteru E.J.; Yulianti R.; Palit C.; Yomaki C.C.; Ahmad S.N.
出版: (2024)

A Systematic Review of the Effects of Bisphenol Analogs on Embryonic Development and Cytoskeletal Organization of Zebrafish (Danio rerio) Embryos
由: 2-s2.0-85127540514
出版: (2023)

NEW RAY ON REMEDIATION OF HIGH RINGS POLYCYCLIC AROMATIC HYDROCARBONS: REMEDIATION OF RAW PETROLEUM SLUDGE USING SOLIDIFICATION AND STABILIZATION METHOD
由: Roslee N.F.; Kamil N.A.F.M.; Kadir A.A.; Jalil A.R.; Hamzah N.; Noor N.M.; Sandu A.V.
出版: (2022)