Enhancing sustained drug release property of chitosan in spheroids through crosslinking reaction and coacervation

Chitosan has not been able to be formulated as sustained-release crosslinked/coacervated drug carrier in the form of spheroids prepared by extrusion-spheronisation technique. This study re-visits chitosan spheroids and their drug (water-soluble chlorpheniramine maleate) release profiles as a functio...

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发表在:Powder Technology
主要作者: 2-s2.0-85068459342
格式: 文件
语言:English
出版: Elsevier B.V. 2019
在线阅读:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85068459342&doi=10.1016%2fj.powtec.2019.07.006&partnerID=40&md5=e52b0510e1ba3b1ea197a265753000eb