Ursodeoxycholic acid upregulates ERK and Akt in the protection of cardiomyocytes against CoCl2

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Ursodeoxycholic acid upregulates ERK and Akt in the protection of cardiomyocytes against CoCl2

Ursodeoxycholic acid (UDCA) is used to treat liver diseases and demonstrates cardioprotective effects. Accumulation of the plasma membrane sphingolipid sphingomyelin in the heart can lead to atherosclerosis and coronary artery disease. Sphingomyelinases (SMases) break down sphingomyelin, producing c...

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Bibliographic Details
Published in:	Genetics and Molecular Research
Main Author:	Hanafi N.I.; Mohamed A.S.; Md Noor J.; Abdul Hamid Hasani N.; Siran R.; Osman N.J.; Ab Rahim S.; Sheikh Abdul Kadir S.H.
Format:	Article
Language:	English
Published:	Fundacao de Pesquisas Cientificas de Ribeirao Preto 2016
Online Access:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85011771016&doi=10.4238%2fgmr.15028150&partnerID=40&md5=b7f8089ab48055aece2c84d849640044

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