Ursodeoxycholic acid protects cardiomyocytes against cobalt chloride induced hypoxia by regulating transcriptional mediator of cells stress hypoxia inducible factor 1α and p53 protein

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Ursodeoxycholic acid protects cardiomyocytes against cobalt chloride induced hypoxia by regulating transcriptional mediator of cells stress hypoxia inducible factor 1α and p53 protein

In hepatocytes, ursodeoxycholic acid (UDCA) activates cell signalling pathways such as p53, intracellular calcium ([Ca2+]i), and sphingosine-1-phosphate (S1P)-receptor via Gαi-coupled-receptor. Recently, UDCA has been shown to protect the heart against hypoxia-reoxygenation injury. However, it is no...

書誌詳細
出版年:	Cell Biochemistry and Function
第一著者:	Mohamed A.S.; Hanafi N.I.; Sheikh Abdul Kadir S.H.; Md Noor J.; Abdul Hamid Hasani N.; Ab Rahim S.; Siran R.
フォーマット:	論文
言語:	English
出版事項:	John Wiley and Sons Ltd 2017
オンライン･アクセス:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85031325768&doi=10.1002%2fcbf.3303&partnerID=40&md5=76edac7ed2f6e599351797d27545b12b

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