Reverse pharmacophore mapping and molecular docking studies for discovery of GTPase HRas as promising drug target for bis-pyrimidine derivatives
Background: Pyrimidine is an important pharmacophore in the field of medicinal chemistry and exhibit a broad spectrum of biological potentials. A study was carried out to identify the target protein of potent bis-pyrimidine derivatives using reverse docking program. PharmMapper, a robust online tool...
| Published in: | Chemistry Central Journal |
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| Main Author: | |
| Format: | Article |
| Language: | English |
| Published: |
BioMed Central Ltd.
2018
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| Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85055212382&doi=10.1186%2fs13065-018-0475-5&partnerID=40&md5=4d1d8f4b504e59917143d823d3a73fec |