Bi-heterocyclic benzamides as alkaline phosphatase inhibitors: Mechanistic comprehensions through kinetics and computational approaches
Novel bi-heterocyclic benzamides were synthesized by sequentially converting 4-(1H-indol-3-yl)butanoic acid (1) into ethyl 4-(1H-indol-3-yl)butanoate (2), 4-(1H-indol-3-yl)butanohydrazide (3), and a nucleophilic 5-[3-(1H-indol-3-yl)propyl]-1,3,4-oxadiazole-2-thiol (4). I...
Published in: | Archiv der Pharmazie |
---|---|
Main Author: | |
Format: | Article |
Language: | English |
Published: |
Wiley-VCH Verlag
2019
|
Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85059670968&doi=10.1002%2fardp.201800278&partnerID=40&md5=5b8723c8342b1711229fed475f428094 |