Biocatalytic modifications of ethynodiol diacetate by fungi, anti-proliferative activity, and acetylcholineterase inhibitory of its transformed products

The fungal transformations of ethynodiol diacetate (1) were investigated for the first-time using Botrytis cinerea, Trichothecium roseum, and R3-2 SP 17. The metabolites obtained are as following: 17α-Ethynyl-17β-acetoxyestr-4-en-3-one-15β-ol (2), 19-nor-17a-ethynyltestosterone (3), and 17α-ethynyl-...

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Bibliographic Details
Published in:Steroids
Main Author: Nurfazilah Wan Yusop S.; Imran S.; Ilham Adenan M.; Ashraf K.; Sultan S.
Format: Article
Language:English
Published: Elsevier Inc. 2021
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85103940287&doi=10.1016%2fj.steroids.2021.108832&partnerID=40&md5=e53e559f125499c7a47e245b1f26ee7f