TRPM4 blocking antibody reduces neuronal excitotoxicity by specifically inhibiting glutamate-induced calcium influx under chronic hypoxia

Excitotoxicity arises from unusually excessive activation of excitatory amino acid receptors such as glutamate receptors. Following an energy crisis, excitotoxicity is a major cause for neuronal death in neurological disorders. Many glutamate antagonists have been examined for their efficacy in miti...

詳細記述

書誌詳細
出版年:Neurobiology of Disease
第一著者: Poore C.P.; Hazalin N.A.M.N.; Wei S.; Low S.W.; Chen B.; Nilius B.; Hassan Z.; Liao P.
フォーマット: 論文
言語:English
出版事項: Academic Press Inc. 2024
オンライン・アクセス:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85182873860&doi=10.1016%2fj.nbd.2024.106408&partnerID=40&md5=7c1fb1b993feb06eb855d715bacc3bfe