Targeted Isolation of Antiviral Labdane Diterpenes from the Bark of Neo-uvaria foetida (Annonaceae) using LC-MS/MS-Based Molecular Networking

In the search of new inhibitors for human coronavirus (HCoV), we screened extracts of endemic Annonaceae plants on an assay using a cellular model of Huh-7 cells infected with the human alphacoronavirus HCoV-229E. The EtOAc bark extract of the rare Southeast Asian plant Neo-uvaria foetida exhibited...

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Bibliographic Details
Published in:Journal of Natural Products
Main Author: Sukumaran S.Y.; Herrscher C.; Rasol N.E.; Othman M.A.; Liew S.Y.; Ismail N.H.; Séron K.; Litaudon M.; Awang K.; El Kalamouni C.; Apel C.; Zahari A.
Format: Article
Language:English
Published: American Chemical Society 2024
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85199047842&doi=10.1021%2facs.jnatprod.4c00342&partnerID=40&md5=14a6ee6a0c48a75d29870fa05c7e54fa