New halogenated chalcones as potential anti-inflammatory agents: A comprehensive In-Silico, In-Vitro, and In-Vivo study with ADME profiling
This study explored the anti-inflammatory potential of halogenated chalcone derivatives using in-silico, in-vitro and in-vivo models. The synthesized compounds were assessed for their ability to inhibit reactive oxygen species (ROS) production and their interaction with the cyclooxygenase-1 (COX-1)...
相似書籍
-
Dexibuprofen loaded into nanoemulsion based gel for topical application – In vitro characterization and in vivo anti-inflammatory evaluation
由: 2-s2.0-85210372378
出版: (2025) -
Virtual screening, ADME study, and molecular dynamic simulation of chalcone and flavone derivatives as 5-Lipoxygenase (5-LO) inhibitor
由: 2-s2.0-85081355590
出版: (2020) -
Investigation of novel benzimidazole-based indole/thiazole hybrids derivatives as effective anti-diabetics and anti-alzheimer's agents: Structure-activity relationship insight, in vitro and in silico approaches
由: 2-s2.0-85193900160
出版: (2024) -
Betamethasone Dipropionate Derivatization, Biotransformation, Molecular Docking, and ADME Analysis as Glucocorticoid Receptor
由: Rashid S.; Anjum S.; Ahmad A.; Nadeem R.; Ahmed M.; Shah S.A.A.; Abdullah M.; Zia K.; Ul-Haq Z.
出版: (2022) -
Molecular modeling and synthesis of novel benzimidazole-derived thiazolidinone bearing chalcone derivatives: A promising approach to develop potential anti-diabetic agents
由: 2-s2.0-85209950182
出版: (2024)