Synthesis of novel N-(1,3-thiazol-2-yl)benzamide clubbed oxadiazole scaffolds: Urease inhibition, Lipinski rule and molecular docking analyses

Present work aimed to synthesize some unique bi-heterocyclic benzamides as lead compounds for the in vitro inhibition of urease enzyme, followed by in silico studies. These targeted benzamides were synthesized in good yields through a multi-step protocol and their struct...

詳細記述

書誌詳細
出版年:Bioorganic Chemistry
第一著者: 2-s2.0-85054810473
フォーマット: 論文
言語:English
出版事項: Academic Press Inc. 2019
オンライン・アクセス:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85054810473&doi=10.1016%2fj.bioorg.2018.10.018&partnerID=40&md5=5ed095fef911fb73da03a549a6c3c914