Synthesis and structure-activity relationship of elastase inhibiting novel ethylated thiazole-triazole acetamide hybrids: Mechanistic insights through kinetics and computational contemplations
Keeping in mind the pharmacological importance of 2-aminothiazole and 1,2,4-triazole heterocyclic moieties, a series of novel ethylated bi-heterocyclic acetamide hybrids, 9a–p, was synthesized in a multi-step protocol. The structures of newly synthesized compounds were c...
發表在: | Bioorganic Chemistry |
---|---|
主要作者: | |
格式: | Review |
語言: | English |
出版: |
Academic Press Inc.
2019
|
在線閱讀: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85060856533&doi=10.1016%2fj.bioorg.2019.01.040&partnerID=40&md5=b1b89e8217b618d2cfdce588785cad50 |