Exploring Acyl Thiotriazinoindole Based Pharmacophores: Design, Synthesis, and SAR Studies with Molecular Docking and Biological Activity Profiling against Urease, α-amylase, α-glucosidase, Antimicrobial, and Antioxidant Targets

A diminutive chemical library of acyl thiotriazinoindole (ATTI) based bioactive scaffolds was synthesized, instigated by taking the economical starting material Isatin, through a series of five steps. Isatin was first nitrated followed by the attachment of pentyl moiety via nucleophilic substitution...

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書目詳細資料
發表在:Protein Journal
主要作者: 2-s2.0-85202972638
格式: Article
語言:English
出版: Springer 2024
在線閱讀:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85202972638&doi=10.1007%2fs10930-024-10229-6&partnerID=40&md5=fb9f13651dd7dd8aa429c4b81bb5a77d