Multitargeted Molecular Docking and Dynamic Simulation Studies of Bioactive Compounds from Rosmarinus officinalis against Alzheimer’s Disease
Alzheimer’s disease (AD) has been associated with the hallmark features of cholinergic dysfunction, amyloid beta (Aβ) aggregation and impaired synaptic transmission, which makes the associated proteins, such as β-site amyloid precursor protein cleaving enzyme 1 (BACE I), acetylcholine esterase (AChE...
出版年: | Molecules |
---|---|
第一著者: | 2-s2.0-85141550803 |
フォーマット: | 論文 |
言語: | English |
出版事項: |
MDPI
2022
|
オンライン・アクセス: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85141550803&doi=10.3390%2fmolecules27217241&partnerID=40&md5=ca002c6ba92d998d2a053c7eb2077bd4 |
類似資料
-
Synthesis, biological evaluation, molecular docking and dynamic simulation of novel benzofuran derivatives as potential agents against Alzheimer's disease
著者:: 2-s2.0-85206074124
出版事項: (2025) -
The β-carboline analogs as a potent inhibitor for Alzheimer's Disease, molecular docking and dynamics simulation study
著者:: 2-s2.0-85173583185
出版事項: (2023) -
Synthesis of benzimidazole–based analogs as anti alzheimer’s disease compounds and their molecular docking studies
著者:: 2-s2.0-85093694209
出版事項: (2020) -
Designing of promising medicinal scaffolds for Alzheimer's disease through enzyme inhibition, lead optimization, molecular docking and dynamic simulation approaches
著者:: 2-s2.0-85070881566
出版事項: (2019) -
Exploration of synthetic multifunctional amides as new therapeutic agents for Alzheimer's disease through enzyme inhibition, chemoinformatic properties, molecular docking and dynamic simulation insights
著者:: 2-s2.0-85053905014
出版事項: (2018)