Ultrastructure of the liver microcirculation influences hepatic and systemic insulin activity and provides a mechanism for age-related insulin resistance

While age-related insulin resistance and hyperinsulinemia are usually considered to be secondary to changes in muscle, the liver also plays a key role in whole-body insulin handling and its role in age-related changes in insulin homeostasis is largely unknown. Here, we show that patent pores called...

Full description

Bibliographic Details
Published in:Aging Cell
Main Author: 2-s2.0-84977636917
Format: Article
Language:English
Published: Blackwell Publishing Ltd 2016
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-84977636917&doi=10.1111%2facel.12481&partnerID=40&md5=b64ffcfebcd96359be9ec2ce8400a7e4