Diversity selection of compounds based on 'protein affinity fingerprints' improves sampling of bioactive chemical space

Diversity selection is a frequently applied strategy for assembling high-throughput screening libraries, making the assumption that a diverse compound set increases chances of finding bioactive molecules. Based on previous work on experimental 'affinity fingerprints', in this study, a nove...

詳細記述

書誌詳細
出版年:Chemical Biology and Drug Design
第一著者: 2-s2.0-84882787252
フォーマット: 論文
言語:English
出版事項: 2013
オンライン・アクセス:https://www.scopus.com/inward/record.uri?eid=2-s2.0-84882787252&doi=10.1111%2fcbdd.12155&partnerID=40&md5=4999a6863c8d20c29853a6f02ad8b77f