Diversity selection of compounds based on 'protein affinity fingerprints' improves sampling of bioactive chemical space

Diversity selection is a frequently applied strategy for assembling high-throughput screening libraries, making the assumption that a diverse compound set increases chances of finding bioactive molecules. Based on previous work on experimental 'affinity fingerprints', in this study, a nove...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:Chemical Biology and Drug Design
المؤلف الرئيسي: 2-s2.0-84882787252
التنسيق: مقال
اللغة:English
منشور في: 2013
الوصول للمادة أونلاين:https://www.scopus.com/inward/record.uri?eid=2-s2.0-84882787252&doi=10.1111%2fcbdd.12155&partnerID=40&md5=4999a6863c8d20c29853a6f02ad8b77f