Diversity selection of compounds based on 'protein affinity fingerprints' improves sampling of bioactive chemical space
Diversity selection is a frequently applied strategy for assembling high-throughput screening libraries, making the assumption that a diverse compound set increases chances of finding bioactive molecules. Based on previous work on experimental 'affinity fingerprints', in this study, a nove...
| Published in: | Chemical Biology and Drug Design |
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| Main Author: | |
| Format: | Article |
| Language: | English |
| Published: |
2013
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| Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84882787252&doi=10.1111%2fcbdd.12155&partnerID=40&md5=4999a6863c8d20c29853a6f02ad8b77f |