Inhibition of prostaglandin E2 production by synthetic minor prenylated chalcones and flavonoids: Synthesis, biological activity, crystal structure, and in silico evaluation

The discovery of potent inhibitors of prostaglandin E2 (PGE 2) synthesis in recent years has been proven to be an important game changer in pharmaceutical industry. It is known that excessive production of PGE2 triggers a vast array of biological signals and physiological events that contributes to...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:Bioorganic and Medicinal Chemistry Letters
المؤلف الرئيسي: 2-s2.0-84905899348
التنسيق: مقال
اللغة:English
منشور في: Elsevier Ltd 2014
الوصول للمادة أونلاين:https://www.scopus.com/inward/record.uri?eid=2-s2.0-84905899348&doi=10.1016%2fj.bmcl.2014.06.061&partnerID=40&md5=621287f1c20ac7c89bdc516f2f4e8182