Benzimidazole derivatives as new α-glucosidase inhibitors and in silico studies

Newly synthesized benzimidazole hydrazone derivatives 1-26 were evaluated for their α-glucosidase inhibitory activity. Compounds 1-26 exhibited varying degrees of yeast α-glucosidase inhibitory activity with IC50 values between 8.40 ± 0.76 and 179.71 ± 1.11 μM when compared with standard acarbose. I...

詳細記述

書誌詳細
出版年:Bioorganic Chemistry
第一著者: 2-s2.0-84948649641
フォーマット: 論文
言語:English
出版事項: Academic Press Inc. 2016
オンライン・アクセス:https://www.scopus.com/inward/record.uri?eid=2-s2.0-84948649641&doi=10.1016%2fj.bioorg.2015.11.006&partnerID=40&md5=93ec464c2d71e54bbd8588cac5d567e0