Reverse pharmacophore mapping and molecular docking studies for discovery of GTPase HRas as promising drug target for bis-pyrimidine derivatives

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Reverse pharmacophore mapping and molecular docking studies for discovery of GTPase HRas as promising drug target for bis-pyrimidine derivatives

Background: Pyrimidine is an important pharmacophore in the field of medicinal chemistry and exhibit a broad spectrum of biological potentials. A study was carried out to identify the target protein of potent bis-pyrimidine derivatives using reverse docking program. PharmMapper, a robust online tool...

書誌詳細
出版年:	Chemistry Central Journal
第一著者:	Kumar S.; Singh J.; Narasimhan B.; Shah S.A.A.; Lim S.M.; Ramasamy K.; Mani V.
フォーマット:	論文
言語:	English
出版事項:	BioMed Central Ltd. 2018
オンライン･アクセス:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85055212382&doi=10.1186%2fs13065-018-0475-5&partnerID=40&md5=4d1d8f4b504e59917143d823d3a73fec

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